Unveiling roles of non‐coding RNAs in cancer through advanced technologies

Non-coding RNAs (ncRNAs) have emerged as key regulators in tumorigenesis. In this perspective, we briefly review the significance of ncRNA in cancer biology and highlight recent technological advancements in characterization of ncRNA in cancer research. Specifically, we discuss how these advanced approaches, such as Patho-DBiT, CRISPR screens, and snoKARR-seq, hold the potential to revolutionize ncRNA research by offering comprehensive insights into their spatial expression patterns and functional roles.

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Publication Details

Journal
Quantitative Biology
Published
2025-04-20
DOI
https://doi.org/10.1002/qub2.70005
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
0.00

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article

Unveiling roles of non‐coding RNAs in cancer through advanced technologies

Leng Han, Runhao Wang
Quantitative Biology
Cancer-related molecular mechanisms research
article

Unveiling roles of non‐coding RNAs in cancer through advanced technologies

Leng Han, Runhao Wang
article en

Abstract

Non-coding RNAs (ncRNAs) have emerged as key regulators in tumorigenesis. In this perspective, we briefly review the significance of ncRNA in cancer biology and highlight recent technological advancements in characterization of ncRNA in cancer research. Specifically, we discuss how these advanced approaches, such as Patho-DBiT, CRISPR screens, and snoKARR-seq, hold the potential to revolutionize ncRNA research by offering comprehensive insights into their spatial expression patterns and functional roles.

Quantitative BiologyVol. 13(4)
Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US)
National Institutes of Health
Openalex Percentile: Top 89%
Cancer-related molecular mechanisms research
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