A Rare Neoplasm of the Kidney: A Female Patient as the First Case Possibly Triggered by Pregnancy

Mixed epithelial and stromal tumor (MEST) is a rare, biphasic adult renal tumor composed of solid and cystic areas with spindle cell stroma and epithelium.Tumors expressing estrogen and progesterone receptors are affected by hormonal changes, often in post-menopausal women on hormone replacement therapy.Since it can be challenging to differentiate between MEST and malignant tumors, it should be considered as a differential diagnosis.To our knowledge, this is the first case postulated to be caused possibly by pregnancy-related hormonal changes.It is noteworthy that the tumor is affected by changing estrogen and progesterone hormone levels during pregnancy, thus rapidly progressing in a brief time.

Authors

Publication Details

Journal
Journal of Urological Surgery
Published
2025-04-21
DOI
https://doi.org/10.4274/jus.galenos.2024.2024-3-10
Primary Topic
Renal and related cancers
Type
article
Field-Weighted Citation Impact
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article

A Rare Neoplasm of the Kidney: A Female Patient as the First Case Possibly Triggered by Pregnancy

Kadir Şerefhan Erten, Serhat Çetin, Melike Urgancı, Mustafa Özgür Tan et al.
Journal of Urological Surgery
Renal and related cancers
article

A Rare Neoplasm of the Kidney: A Female Patient as the First Case Possibly Triggered by Pregnancy

Kadir Şerefhan Erten, Serhat Çetin, Melike Urgancı, Mustafa Özgür Tan, İpek Işık Gönül
article en

Abstract

Mixed epithelial and stromal tumor (MEST) is a rare, biphasic adult renal tumor composed of solid and cystic areas with spindle cell stroma and epithelium.Tumors expressing estrogen and progesterone receptors are affected by hormonal changes, often in post-menopausal women on hormone replacement therapy.Since it can be challenging to differentiate between MEST and malignant tumors, it should be considered as a differential diagnosis.To our knowledge, this is the first case postulated to be caused possibly by pregnancy-related hormonal changes.It is noteworthy that the tumor is affected by changing estrogen and progesterone hormone levels during pregnancy, thus rapidly progressing in a brief time.

Journal of Urological Surgery
Gender equality
Openalex Percentile: Top 93%
Renal and related cancers
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A Rare Neoplasm of the Kidney: A Female Patient as the First Case Possibly Triggered by Pregnancy — Kadir Şerefhan Erten, Serhat Çetin, et al. · Journal of Urological Surgery (2025) | TGRS Research Map | TGRS