The correlation between periostin and <i>eosinophillic cationic protein</i> demonstrate its potential biomarker of mucosal remodeling in chronic rhinosinusitis with nasal polyps

Periostin is significantly elevated in nasal polyps, highlighting its role in CRSwNP. Its correlation with ECP in the uncinate process suggests involvement in inflammation, warranting further research into periostin as a therapeutic target. This study confirms periostin's role in CRSwNP, it potentially occurs with or without depending on the CRS endotype pathways.