D-dimer as a risk factor for cardiovascular events in patients with liver diseases

The relationship between cardiovascular and liver diseases is a significant clinical problem; since diseases of one system can aggravate the other. One of the key markers for cardiovascular risk assessment in patients with liver diseases is D-dimer. This is a fibrin degradation product; the level of which increases with the coagulation system activation. It is important to note the role of ademetionine (Heptral®) in supporting liver function; reducing inflammation and oxidative stress; which can reduce the development and progression of atherosclerosis and cardiovascular complications in patients with liver disease. Determination of D-dimer is important in risk stratification and assessment of clinical outcomes in patients with liver and cardiovascular comorbidity; including those treated with ademetionine.