Initial gut microbiota composition is a determining factor in the promotion of colorectal cancer by oral iron supplementation: evidence from a murine model
Our findings suggest that microbiota-targeted interventions may mitigate tumorigenic effects of iron supplementation in anemic patients with CRC.
Authors
- Frank Schwenter (ORCID: https://orcid.org/0000-0002-4290-138X)
- Marianne Gagnon-Konamna
- François Dagbert (ORCID: https://orcid.org/0000-0002-3705-8164)
- Herawaty Sebajang (ORCID: https://orcid.org/0000-0001-8848-0392)
- Ramses Wassef
- Rasmy Loungnarath (ORCID: https://orcid.org/0009-0001-9959-1212)
- Éric De Broux (ORCID: https://orcid.org/0000-0002-7056-0500)
- Roy Hajjar
- Hervé Vennin Rendos (ORCID: https://orcid.org/0009-0004-5091-6866)
- Annie Calvé (ORCID: https://orcid.org/0000-0001-7653-9035)
- Nassima Taleb (ORCID: https://orcid.org/0009-0009-8786-1949)
- Richard Ratelle (ORCID: https://orcid.org/0009-0005-7003-1704)
- Gabriela Fragoso (ORCID: https://orcid.org/0000-0001-7004-4939)
- Manuela M. Santos (ORCID: https://orcid.org/0000-0003-3497-0585)
- Thibault Cuisiniere (ORCID: https://orcid.org/0000-0001-7325-9476)
- Claire Gerkins (ORCID: https://orcid.org/0000-0003-1121-3362)
- Manon Oliero
- Carole Richard
Institutions
- Université de Montréal (CA)
Publication Details
- Journal
- Microbiome
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1186/s40168-025-02101-1
- Citations
- 6
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.84
Funders
- Génome Québec
- Ministère de la Santé et des Services sociaux
- Ministère de la Santé
- Université de Montréal
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada