PTGS2 Silencing Inhibits Ferroptosis in Staphylococcus Aureus-induced Osteomyelitis By Blocking the IL-17A Signaling Pathway
Silencing PTGS2 reduces ferroptosis in S. aureus-induced osteomyelitis by obstructing the IL-17A pathway, which suggests a new approach for the treatment of osteomyelitis.
Authors
- Huazhang Xiong (ORCID: https://orcid.org/0000-0002-1017-5109)
- Jiachen Peng (ORCID: https://orcid.org/0000-0001-7267-0650)
- Sirui Zhou (ORCID: https://orcid.org/0000-0003-4963-0815)
- Hao Xiang (ORCID: https://orcid.org/0000-0001-5691-0140)
- Lidan Yang (ORCID: https://orcid.org/0000-0002-2354-257X)
- Jianbo Feng (ORCID: https://orcid.org/0000-0002-0634-9647)
- Wenguang Li (ORCID: https://orcid.org/0000-0001-9622-396X)
- Ying Jin (ORCID: https://orcid.org/0009-0008-7146-5362)
Institutions
- Zunyi Medical University (CN)
- Dalian Medical University (CN)
- First People’s Hospital of Zunyi (CN)
Publication Details
- Journal
- Inflammation
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1007/s10753-025-02296-3
- Citations
- 2
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.61