A comparative evaluation of salivary and plasma bisphenol-A levels in patients released from four different orthodontic appliances: ultra-performance liquid chromatography–mass spectrometry study. A non-randomized clinical trial

This research obviously demonstrated that the orthodontic appliances we investigated release BPA into the saliva. However, the BPA levels detected in both saliva and plasma are consistently within the acceptable safety limits. However, precautions should be taken to minimize BPA release during orthodontic treatment.