Safety and efficacy of robotic-assisted laparoscopic pyeloplasty for ureteropelvic junction obstruction in infants under 6 months

To evaluate the safety and efficacy of robotic-assisted laparoscopic pyeloplasty (RALP) in infants under 6 months of age with ureteropelvic junction obstruction (UPJO). A retrospective analysis was conducted on infants aged ≤ 6 months who underwent RALP for UPJO between March 2021 and June 2024. Surgical indications included ultrasonographic evidence of severe hydronephrosis, progressive postnatal hydronephrosis, or symptoms related to hydronephrosis compression. Data on demographic characteristics, surgical details, postoperative complications, and follow-up outcomes were analyzed. Among 52 infants (34 male, 18 female), the median age was 70 days (IQR: 45, 107; 95% CI: 61, 87) and mean weight was 5.90 ± 1.39 kg (95% CI: 5.5, 6.3). All procedures were completed robotically without conversion. The mean operative time was 189 ± 34 min (95% CI: 177, 197) with median blood loss of 8.5 mL (IQR: 6.4, 11.3; 95% CI: 7.7, 9.7). Double-J stent placement (4.7 F) was successful in all cases. The median hospital stay was 4.0 days (IQR: 3.0, 4.0; 95% CI: 3.0, 4.0). Postoperative complications occurred in 7 patients (13.5%), including Clavien-Madadi grade I (n = 2), II (n = 4), and III (n = 1). At 3-month follow-up, the mean anteroposterior diameter (APD) decreased from 30.6 ± 8.6 mm to 11.8 ± 6.8 mm (P < 0.0001), and the mean parenchymal thickness increased from 2.4 ± 1.2 mm to 6.6 ± 2.1 mm (P < 0.0001). Success rate was 100% at median follow-up of 21 months (IQR: 16, 26; 95% CI: 19,23). RALP represents a safe and effective treatment option for UPJO in infants age ≤ 6 months, demonstrating excellent short-term outcomes and acceptable complication rates.

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Publication Details

Journal
Scientific Reports
Published
2025-04-21
DOI
https://doi.org/10.1038/s41598-025-99115-4
Citations
4
Primary Topic
Pediatric Urology and Nephrology Studies
Type
article
Field-Weighted Citation Impact
13.98

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article

Safety and efficacy of robotic-assisted laparoscopic pyeloplasty for ureteropelvic junction obstruction in infants under 6 months

Jianxi Gao, Lin Wang, Xiaohui Wang, Shufeng Zhang
4 citations
Scientific Reports
Pediatric Urology and Nephrology Studies
13.98
article

Safety and efficacy of robotic-assisted laparoscopic pyeloplasty for ureteropelvic junction obstruction in infants under 6 months

Jianxi Gao, Lin Wang, Xiaohui Wang, Shufeng Zhang
article en
4 citations

Abstract

To evaluate the safety and efficacy of robotic-assisted laparoscopic pyeloplasty (RALP) in infants under 6 months of age with ureteropelvic junction obstruction (UPJO). A retrospective analysis was conducted on infants aged ≤ 6 months who underwent RALP for UPJO between March 2021 and June 2024. Surgical indications included ultrasonographic evidence of severe hydronephrosis, progressive postnatal hydronephrosis, or symptoms related to hydronephrosis compression. Data on demographic characteristics, surgical details, postoperative complications, and follow-up outcomes were analyzed. Among 52 infants (34 male, 18 female), the median age was 70 days (IQR: 45, 107; 95% CI: 61, 87) and mean weight was 5.90 ± 1.39 kg (95% CI: 5.5, 6.3). All procedures were completed robotically without conversion. The mean operative time was 189 ± 34 min (95% CI: 177, 197) with median blood loss of 8.5 mL (IQR: 6.4, 11.3; 95% CI: 7.7, 9.7). Double-J stent placement (4.7 F) was successful in all cases. The median hospital stay was 4.0 days (IQR: 3.0, 4.0; 95% CI: 3.0, 4.0). Postoperative complications occurred in 7 patients (13.5%), including Clavien-Madadi grade I (n = 2), II (n = 4), and III (n = 1). At 3-month follow-up, the mean anteroposterior diameter (APD) decreased from 30.6 ± 8.6 mm to 11.8 ± 6.8 mm (P < 0.0001), and the mean parenchymal thickness increased from 2.4 ± 1.2 mm to 6.6 ± 2.1 mm (P < 0.0001). Success rate was 100% at median follow-up of 21 months (IQR: 16, 26; 95% CI: 19,23). RALP represents a safe and effective treatment option for UPJO in infants age ≤ 6 months, demonstrating excellent short-term outcomes and acceptable complication rates.

Scientific ReportsVol. 15(1)
Zhengzhou University (CN), Zhengzhou People's Hospital (CN)
Henan Provincial Science and Technology Research Project
Good health and well-being
Openalex Percentile: Top 1%
Pediatric Urology and Nephrology Studies
13.98
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