Evaluation of Pharmacists' Knowledge on Antibiotic Use in Kidney Failure in Rada'a, Yemen

Abstract Background: Kidney failure is an important health problem that affects millions of people around the world. Chronic renal failure (CRF) represents kidney damage resulting from early- to end-stage renal disease (ESRD) and is a major public health condition worldwide, Among the treatments used are antibiotics. Antibiotics are vital medicines used to fight and treat bacterial infections. Although these medications are effective in treating infections, their improper use can lead to serious health problems, including increased drug resistance. Community pharmacies play a crucial role in providing antibiotics and guiding patients on their safe and appropriate use Aim: This research seeks to assess pharmacists' understanding of antibiotic usage in patients with kidney failure in Rada'a Town. Methods: A cross-sectional study design was utilized in community pharmacies situated in Rada'a Town. A convenience sample consisting of 68 pharmacists was chosen. Data collection was conducted through a structured closed questionnaire, which was later analyzed using SPSS software. Results: The participant group was predominantly male (86.8%), with 47.1% of respondents being under 25 years old. Most participants (47.1%) had between 1 to 5 years of professional experience, and 64.7% held a diploma. The pharmacists exhibited a commendable level of knowledge regarding chronic kidney disease (84.1%) and awareness of the condition itself (71.3%). Amoxicillin was found to be the most frequently prescribed antibiotic deemed safe (72.1%), while Vancomycin was recognized as the most commonly prescribed antibiotic considered unsafe (60.3%). Conclusion: The findings show a moderate awareness of chronic kidney disease among pharmacists in Rada'a Town. While Amoxicillin is commonly prescribed as a safe antibiotic, Vancomycin is seen as unsafe. Many pharmacists showed uncertainty about various antibiotics, indicating a need for better education. Overall, awareness is adequate, but significant improvements are necessary. Keywords: Chronic Kidney Disease, Antibiotic Safety, Awareness, Pharmacy Practice, Patient Care.