Familial Thoracic Aortic Aneurysm and Dissection: Simultaneous Presentation in Two Brothers

Familial thoracic aortic aneurysm and dissection (FTAAD) is an inherited condition with variable penetrance, often leading to life-threatening aortic events. We report the cases of two Jamaican brothers who developed acute aortic dissections following the death of a sibling from FTAAD. We reviewed recent literature regarding patient demographics, genetic variability, diagnostic modalities, and management strategies for similar cases. Despite the availability of guidelines, early identification of at-risk individuals and specific management strategies are essential to prevent life-threatening events.

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Publication Details

Journal
Cureus
Published
2025-04-21
DOI
https://doi.org/10.7759/cureus.82697
Primary Topic
Aortic Disease and Treatment Approaches
Type
article
Field-Weighted Citation Impact
0.00
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article

Familial Thoracic Aortic Aneurysm and Dissection: Simultaneous Presentation in Two Brothers

Adesoji Adenigbagbe, Kyle Maisel, Kunal Karmilkar, Lis M Llanio
Cureus
Aortic Disease and Treatment Approaches
article

Familial Thoracic Aortic Aneurysm and Dissection: Simultaneous Presentation in Two Brothers

Adesoji Adenigbagbe, Kyle Maisel, Kunal Karmilkar, Lis M Llanio
article en

Abstract

Familial thoracic aortic aneurysm and dissection (FTAAD) is an inherited condition with variable penetrance, often leading to life-threatening aortic events. We report the cases of two Jamaican brothers who developed acute aortic dissections following the death of a sibling from FTAAD. We reviewed recent literature regarding patient demographics, genetic variability, diagnostic modalities, and management strategies for similar cases. Despite the availability of guidelines, early identification of at-risk individuals and specific management strategies are essential to prevent life-threatening events.

CureusVol. 17(4)
Nova Southeastern University (US), Planta (RU), Northwest Hospital (US)
Openalex Percentile: Top 87%
Aortic Disease and Treatment Approaches
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