Müllerian Remnants in Appendix: A Case of Adolescent Appendiceal Endosalpingiosis
<b>Background:</b> Endosalpingiosis, a condition characterized by the presence of fallopian tube-like epithelium outside the tubes, is an incidental finding in histopathological examinations. The pathogenesis of this condition is a subject of debate, with various theories proposed to explain its origin. Its association with tumors of Müllerian origin has been observed. <b>Case report:</b> We describe an 11-year-old girl, the second adolescent case of appendiceal endosalpingiosis documented to date, who presented with symptoms suggestive of appendicitis and underwent laparoscopic appendectomy, with histopathological examination confirming the diagnosis. <b>Conclusion:</b> Our case suggests that endosalpingiosis may be indicative of müllerian choristomas. The potential link between endosalpingiosis and gynecological malignancies is concerning. Further studies are needed to elucidate the clinical significance of appendiceal endosalpingiosis in relation to gynecologic malignancies.
Authors
- Jing Zhao (ORCID: https://orcid.org/0000-0002-3208-9009)
- Yangyang Ma (ORCID: https://orcid.org/0000-0002-3617-9941)
- Jiayan Feng
- Di Ding
- Feng Tian (ORCID: https://orcid.org/0000-0002-9118-4460)
Institutions
- Children's Hospital of Fudan University (CN)
Publication Details
- Journal
- Fetal and Pediatric Pathology
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1080/15513815.2025.2493129
- Primary Topic
- Intraperitoneal and Appendiceal Malignancies
- Type
- article
- Field-Weighted Citation Impact
- 0.00