Identification of Distinguishing Features of Drug‐Induced Liver Injury and Liver Injury Associated With Sepsis

Marked elevation of AST and rapid resolution with a HC pattern of liver injury favours the diagnosis of SILI. Cholestatic/mixed SILI also resolves rapidly in contrast to CS/mixed DILI that is associated with markers of more pronounced liver injury.

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Publication Details

Journal
Liver International
Published
2025-04-21
DOI
https://doi.org/10.1111/liv.70090
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of Distinguishing Features of Drug‐Induced Liver Injury and Liver Injury Associated With Sepsis

Sigrún H. Lund, Sigurbergur Kárason, Edda Vésteinsdóttir, Einar Stefan Bjornsson et al.
Liver International
Drug-Induced Hepatotoxicity and Protection
article

Identification of Distinguishing Features of Drug‐Induced Liver Injury and Liver Injury Associated With Sepsis

Sigrún H. Lund, Sigurbergur Kárason, Edda Vésteinsdóttir, Einar Stefan Bjornsson, Guruprasad Padur Aithal, Sigurdur S. Sigurdarson, Egill Logason, Robert Alexander Bjornsson
article en

Abstract

Marked elevation of AST and rapid resolution with a HC pattern of liver injury favours the diagnosis of SILI. Cholestatic/mixed SILI also resolves rapidly in contrast to CS/mixed DILI that is associated with markers of more pronounced liver injury.

Liver InternationalVol. 45(5)
Nottingham University Hospitals NHS Trust (GB), University of Nottingham (GB), University of Iceland (IS), National University Hospital of Iceland (IS), Nottingham Biomedical Research Centre (GB)
Good health and well-being
Openalex Percentile: Top 90%
Drug-Induced Hepatotoxicity and Protection
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Identification of Distinguishing Features of Drug‐Induced Liver Injury and Liver Injury Associated With Sepsis — Sigrún H. Lund, Sigurbergur Kárason, et al. · Liver International (2025) | TGRS Research Map | TGRS