Langerhans cell histiocytosis of the jaw: clinical analysis of 68 cases
JLCH can affect individuals of all ages, though it is more common in children. Factors such as gender, lesion multiplicity, and lesion type (alveolar) are significant in predicting disease progression. Complete surgical resection combined with radiotherapy offers the highest likelihood of cure for SS-type JLCH.
Authors
- Jiannan Liu
- Hao Wu (ORCID: https://orcid.org/0000-0002-4934-6921)
- Jinchen Li (ORCID: https://orcid.org/0009-0002-3893-8128)
- Jing Han (ORCID: https://orcid.org/0000-0003-1754-6782)
- Zilin Wang (ORCID: https://orcid.org/0009-0007-8318-8422)
- Bing Han (ORCID: https://orcid.org/0000-0003-4296-2606)
Institutions
- Shanghai Jiao Tong University (CN)
- Jilin University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Shanghai Stomatological Hospital (CN)
- Shanghai Ninth People's Hospital (CN)
Publication Details
- Journal
- Orphanet Journal of Rare Diseases
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1186/s13023-025-03680-w
- Primary Topic
- Histiocytic Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shanghai Key Laboratory of Intelligent Information Processing