Carboxymethyl-lysine is a Prominent Target of Circulating IgA in IgA Nephropathy
Our studies identify CML as a primary target of circulating IgA in IgAN, suggesting that aberrant responses to this modified self-antigen contribute to disease pathophysiology.
Authors
- Emmanuel Zorn (ORCID: https://orcid.org/0000-0001-9985-8389)
- Talita Ferreira Marques Aguiar (ORCID: https://orcid.org/0000-0003-0202-6848)
- Paolo Cravedi (ORCID: https://orcid.org/0000-0001-7837-0923)
- Sara Alibrandi (ORCID: https://orcid.org/0000-0001-6463-6057)
- Maria Lanau
- Paolo Molinari (ORCID: https://orcid.org/0000-0001-6196-5656)
- Joaquín Manrique (ORCID: https://orcid.org/0000-0002-7713-1629)
- Nicholas Chun (ORCID: https://orcid.org/0000-0001-6884-3686)
- Umberto Maggiore (ORCID: https://orcid.org/0000-0002-7468-9600)
- Enrico Fiaccadori (ORCID: https://orcid.org/0000-0002-6532-7675)
- Mattea Ausmeier
- Mario Perez-Arnedo
Institutions
- University of Parma (IT)
- Columbia University Irving Medical Center (US)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Complejo Hospitalario de Navarra (ES)
- Martin Luther University Halle-Wittenberg (DE)
- Universidad de Navarra (ES)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1016/j.ekir.2025.04.016
- Citations
- 2
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 2.86