Multiple Epidermodysplasia Verruciformis Successfully Treated by Surgery Combined with Photodynamic Therapy

<b><i>Objective:</i></b> To explore an effective treatment for extensive and multiple epidermodysplasia verruciformis (EV). <b><i>Methods:</i></b> A 30-year-old female with a 10-year history of EV lesions underwent surgery to remove verrucous plaques and residual lesions, followed by photodynamic therapy once a week for three times. <b><i>Results:</i></b> After a one-year follow-up, no recurrence was observed, and the patient was satisfied with the outcome. <b><i>Conclusion:</i></b> Surgery combined with photodynamic therapy seems promising for treating extensive and multiple EV, but more research is needed for verification.