Defining the noma research agenda
• A 1-day symposium brought together over 100 individuals with lived experience of noma, expertise in neglected tropical diseases, and public health, including researchers, health advocates, and clinicians. The involvement of noma survivors was invaluable and added an important perspective in defining the research agenda. • The most pressing research needs identified were: ○ Clear case definition of noma ○ Early case detection and robust surveillance ○ Psychosocial and economic impact of noma ○ Decision support for diagnosing acute necrotizing gingivitis and associated antibiotic regimen(s) with treatment duration ○ Deeper understanding of risk factors and social determinants ○ Identification of effective information, education, and communication strategies ○ Effectiveness of surgical services ○ Testing decentralized follow-up for patients • An important conclusion was that noma research and control activities must be integrated across sectors and disciplines, such as neglected tropical diseases, oral health, nutrition, and child health programs including immunization.
Authors
- Peter Steinmann (ORCID: https://orcid.org/0000-0003-4800-3019)
- Philippe J. Guérin (ORCID: https://orcid.org/0000-0002-6008-2963)
- Mark Sherlock (ORCID: https://orcid.org/0000-0003-4078-624X)
- Jürg Utzinger (ORCID: https://orcid.org/0000-0001-6885-0798)
- Anaïs Galli (ORCID: https://orcid.org/0000-0002-5533-3211)
- Emmanuel Kabengele Mpinga (ORCID: https://orcid.org/0000-0002-5763-4843)
- Marta Ribes (ORCID: https://orcid.org/0000-0001-7269-1507)
- Manuel W. Hetzel (ORCID: https://orcid.org/0000-0002-5285-3254)
- Erika Placella
- Denise Baratti-Mayer (ORCID: https://orcid.org/0000-0003-3005-8935)
- Daniel Argaw Dagne
- Maria Guevara
- Thi H. Cao (ORCID: https://orcid.org/0000-0002-2451-0342)
- Valter Muendane
- Mulikat Okanlawon
- Marianne Comparet
- Claire Jeantet
Institutions
- University of Geneva (CH)
- Drugs for Neglected Diseases Initiative (CH)
- Swiss Tropical and Public Health Institute (CH)
- University of Basel (CH)
- University of Oxford (GB)
- Hôpital Beau-Séjour (CH)
- World Health Organization (CH)
- Asur Plant Breeding (France) (FR)
- Médecins Sans Frontières (CH)
- Médecins Sans Frontières (NL)
- Barcelona Institute for Global Health (ES)
- Infectious Diseases Data Observatory (GB)
- Swiss Agency for Development and Cooperation
- Universitat de Barcelona (ES)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1371/journal.pntd.0012940
- Citations
- 3
- Primary Topic
- HIV/AIDS oral health manifestations
- Type
- article
- Field-Weighted Citation Impact
- 5.64