Cutaneous Implications of Liver Cirrhosis: A Case of Acrodermatitis Enteropathica

Acrodermatitis enteropathica (AE) is characterized by a constellation of symptoms that result from a deficiency in serum zinc levels. The commonest cause of AE is hereditary autosomal recessive genetic mutations that impair zinc absorption in the small intestine, while acquired causes come second. Liver disease has been implicated in the development of acquired zinc deficiency. Herein, we present a case of AE with severe exfoliative skin lesions that occurred secondary to decompensated liver cirrhosis.

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Publication Details

Journal
Cureus
Published
2025-04-21
DOI
https://doi.org/10.7759/cureus.82734
Primary Topic
Prion Diseases and Protein Misfolding
Type
article
Field-Weighted Citation Impact
0.00
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article

Cutaneous Implications of Liver Cirrhosis: A Case of Acrodermatitis Enteropathica

Caley McIntyre, Justin H. Nguyen, Sameera Shuaibi, Samer Farhud et al.
1 links
Cureus
Prion Diseases and Protein Misfolding
article

Cutaneous Implications of Liver Cirrhosis: A Case of Acrodermatitis Enteropathica

Caley McIntyre, Justin H. Nguyen, Sameera Shuaibi, Samer Farhud, Najat AlSejari
article en

Abstract

Acrodermatitis enteropathica (AE) is characterized by a constellation of symptoms that result from a deficiency in serum zinc levels. The commonest cause of AE is hereditary autosomal recessive genetic mutations that impair zinc absorption in the small intestine, while acquired causes come second. Liver disease has been implicated in the development of acquired zinc deficiency. Herein, we present a case of AE with severe exfoliative skin lesions that occurred secondary to decompensated liver cirrhosis.

CureusVol. 17(4)
Ochsner Medical Center (US)
Openalex Percentile: Top 93%
Prion Diseases and Protein Misfolding
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