Adult-Onset Immunoglobulin A Vasculitis (IgAV) Presenting in a Middle-Aged Indian Male Patient

Immunoglobulin A vasculitis (IgAV) is a small vessel vasculitis that mainly affects the skin, gastrointestinal tract, and kidneys. We present a case of a middle-aged male patient who presented to the emergency department with lower chest pain, colicky abdominal pain, and painful petechial rash. His inflammatory markers and IgA were raised with mild proteinuria. Abdominal CT and endoscopy revealed gastrointestinal involvement, and immunofluorescence skin biopsy confirmed IgA deposition in the dermal vessels. He responded clinically to oral steroids, and his inflammatory markers trended down. After six days, he was discharged.

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Publication Details

Journal
Cureus
Published
2025-04-21
DOI
https://doi.org/10.7759/cureus.82735
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Adult-Onset Immunoglobulin A Vasculitis (IgAV) Presenting in a Middle-Aged Indian Male Patient

Evelyn Chang, Abdalla Khalil, Naomi Oldham, Saju Beepaul
Cureus
Vasculitis and related conditions
article

Adult-Onset Immunoglobulin A Vasculitis (IgAV) Presenting in a Middle-Aged Indian Male Patient

Evelyn Chang, Abdalla Khalil, Naomi Oldham, Saju Beepaul
article en

Abstract

Immunoglobulin A vasculitis (IgAV) is a small vessel vasculitis that mainly affects the skin, gastrointestinal tract, and kidneys. We present a case of a middle-aged male patient who presented to the emergency department with lower chest pain, colicky abdominal pain, and painful petechial rash. His inflammatory markers and IgA were raised with mild proteinuria. Abdominal CT and endoscopy revealed gastrointestinal involvement, and immunofluorescence skin biopsy confirmed IgA deposition in the dermal vessels. He responded clinically to oral steroids, and his inflammatory markers trended down. After six days, he was discharged.

CureusVol. 17(4)
Northwick Park Hospital (GB), Northwick Park Institute for Medical Research (GB)
Gender equality
Openalex Percentile: Top 87%
Vasculitis and related conditions
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