Intergenerational and transgenerational reproductive toxicity of polystyrene microplastics in female mice

Evidence continues to emerge on the reproductive hazards induced by microplastics (MPs) in humans and animals. However, conclusive evidence for the reproductive toxicity of MPs in human contexts is still limited, and understanding the intergenerational and transgenerational reproductive toxicity of MPs in mammals remains elusive. In this report, we found evidence that lactating exposure to 1 μm of MPs (a similar dose that human infants are exposed to during artificial feeding), induced reproductive toxicity in female mice and their offspring.