Spinal Hemangioblastoma: The Role of Imaging Characteristics in Preoperative Diagnosis and Surgical Planning

Spinal hemangioblastomas are rare, highly vascular tumors of the central nervous system (CNS) that may occur sporadically or in association with von Hippel-Lindau disease. These tumors pose significant diagnostic and surgical challenges due to their intramedullary location and propensity for hemorrhage. Given their radiographic overlap with other spinal cord tumors, imaging plays a crucial role in preoperative diagnosis and surgical planning. We present the case of a 58-year-old woman who developed progressive left lower limb weakness and sensory impairment over two years. Magnetic resonance imaging (MRI) revealed a lobulated, heterogeneously enhancing solid-cystic lesion within the spinal canal at the T11-12 level, with a diffuse syrinx spanning the entire cord. Surgical resection was performed, with a highly vascular lesion encountered intraoperatively. Histopathology confirmed the diagnosis of hemangioblastoma, classified as World Health Organization (WHO) grade 1. Reviewing the literature, certain radiographic features can aid in the diagnosis of spinal hemangioblastomas, improving preoperative planning for patients with these tumors. Surgical implications include the contraindication to biopsy due to the tumor's vascularity, as well as preparation of blood products and preoperative patient counseling.

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Publication Details

Journal
Cureus
Published
2025-04-21
DOI
https://doi.org/10.7759/cureus.82740
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
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article

Spinal Hemangioblastoma: The Role of Imaging Characteristics in Preoperative Diagnosis and Surgical Planning

Char Loo Tan, Shiong Wen Low, Su Lone Lim, Chun Peng Goh et al.
Cureus
Cancer, Hypoxia, and Metabolism
article

Spinal Hemangioblastoma: The Role of Imaging Characteristics in Preoperative Diagnosis and Surgical Planning

Char Loo Tan, Shiong Wen Low, Su Lone Lim, Chun Peng Goh, Ira Sun, Z. Zhang
article en

Abstract

Spinal hemangioblastomas are rare, highly vascular tumors of the central nervous system (CNS) that may occur sporadically or in association with von Hippel-Lindau disease. These tumors pose significant diagnostic and surgical challenges due to their intramedullary location and propensity for hemorrhage. Given their radiographic overlap with other spinal cord tumors, imaging plays a crucial role in preoperative diagnosis and surgical planning. We present the case of a 58-year-old woman who developed progressive left lower limb weakness and sensory impairment over two years. Magnetic resonance imaging (MRI) revealed a lobulated, heterogeneously enhancing solid-cystic lesion within the spinal canal at the T11-12 level, with a diffuse syrinx spanning the entire cord. Surgical resection was performed, with a highly vascular lesion encountered intraoperatively. Histopathology confirmed the diagnosis of hemangioblastoma, classified as World Health Organization (WHO) grade 1. Reviewing the literature, certain radiographic features can aid in the diagnosis of spinal hemangioblastomas, improving preoperative planning for patients with these tumors. Surgical implications include the contraindication to biopsy due to the tumor's vascularity, as well as preparation of blood products and preoperative patient counseling.

CureusVol. 17(4)
Nanyang Technological University (SG), Ng Teng Fong General Hospital (SG), National University Hospital (SG)
Openalex Percentile: Top 89%
Cancer, Hypoxia, and Metabolism
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Spinal Hemangioblastoma: The Role of Imaging Characteristics in Preoperative Diagnosis and Surgical Planning — Char Loo Tan, Shiong Wen Low, et al. · Cureus (2025) | TGRS Research Map | TGRS