Micropolycystic Ovary Syndrome: Phenotypes, Clinical and Ultrasound Profile of Infertile Patients in Butembo/Eastern DRC

Introduction: Micropolycystic ovary syndrome (MPCOS) is one of the most common endocrine disorders in women. The aim of the study was to determine the phenotypes and the clinical and ultrasound profile of MPCOS in infertile patients in Butembo. Methods: The study was a multicentre, cross-sectional, analytical study conducted in the city of Butembo. It included 89 married infertile patients with MPCOS, aged 20 to 45 years, without hyperprolactinaemia, selected according to the Rotterdam criteria of 2003; 89 infertile patients without MPCOS were matched. Data analysis was performed using R software version 4.4.1. Results: Phenotype A was the most common with 34.8% of patients, followed by phenotype C with 28.1%. Nulliparity (48.3%), oligomenorrhoea (42.7%), hirsutism (86.5%) and acne (61.8%) were significantly associated with MPCOS (p 0.001). In multivariate logistic regression analysis of gynaecological characteristics, nulliparity (OR = 6.75 [95% CI = 2.24 - 22.5], p 0.001). Conclusion: Phenotype A is the most common among infertile patients in the town of Butembo, followed by phenotype C, phenotype B and phenotype D. The clinical profile is dominated by oligomenorrhoea, hirsutism, acne and nulliparity. The ultrasound profile of patients with MPCOS is characterised by increased ovarian volume.