Vacuole and mitochondria patch protein Mcp1 of Saccharomyces boulardii impairs the oxidative stress response of Candida albicans by regulating 2-phenylethanol
This work reveals the critical role of Mcp1 in S. boulardii against C. albicans by regulating 2-phenylethanol metabolism, which provide a theoretical basis for S. boulardii as antifungal biologic therapy to prevent and treat of Candida infection.
Authors
- Junjie Fu (ORCID: https://orcid.org/0000-0002-1528-8727)
- Xiaohui Zhao (ORCID: https://orcid.org/0000-0001-6852-0975)
- Xiaolong Mao (ORCID: https://orcid.org/0000-0001-7246-4195)
- Yunyun Wei
- Chuanqi Li (ORCID: https://orcid.org/0000-0001-8254-5319)
- Wanli Gao
Institutions
- Shandong First Medical University (CN)
Publication Details
- Journal
- Microbial Cell Factories
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1186/s12934-025-02721-0
- Citations
- 2
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province