Abstract 7390: Differences in cancer and all cause mortality among non Hispanic Black American adults by nativity and duration of U.S. residence: Findings from the 1997-2018 NHIS-NDI record linkage study

Abstract Background: Non-Hispanic Black (NHB) Americans bear a high burden of cancer and all-cause mortality. Previous studies show that foreign-born individuals generally have lower cancer mortality rates, though declines are more pronounced among U.S.-born NHBs. This study examined differences in cancer and all-cause mortality risk between U.S.-born and foreign-born NHB adults, as well as by duration of U.S. residence among the foreign-born. Method: We used pooled data from the 1997–2018 National Health Interview Survey, linked to the National Death Index with follow-up through December 31, 2019, including 90,487 adult NHB participants. Cox regression models were used to estimate hazard ratios by place of birth and duration of residence in the U.S. after adjusting for sociodemographic and health behavior factors. Result: Among participants (61.1% women, mean age 46.5), 90.6% were U.S.-born, with an average follow-up of 10.9 years. U.S.-born individuals had a higher cancer mortality risk compared to foreign-born individuals (women: aHR 1.61; 95% CI 1.22–2.13 and men: aHR 1.33; 95% CI 1.04–1.69). For all-cause mortality, U.S.-born women (aHR = 1.64, 95% CI: 1.44–1.87) and men (aHR = 1.54, 95% CI: 1.35–1.75) had similarly increased risks. No significant differences in all-cause and cancer mortality were observed by duration of U.S. residence among foreign-born NHB adults. Conclusion: The intra-racial disparity in cancer and all-cause mortality has been continuously observed over the past several decades. Multi-pronged research strategies are needed to understand this disparity as well as to plan appropriate interventions to close this gap. Citation Format: Aminu K. Abubakar, Phoung T. Nguyen, Mahbubur Rahman. Differences in cancer and all cause mortality among non Hispanic Black American adults by nativity and duration of U.S. residence: Findings from the 1997-2018 NHIS-NDI record linkage study [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr 25-30; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2025;85(8_Suppl_1):Abstract nr 7390.