The profiling and analysis of gene expression in rat temporomandibular joint disc tissue and its derived cells
Collagen types VI and II were prominently expressed, followed by collagen types I and III, in TMJ disc tissues, reflecting the unique functions of the disc. Type VI collagen was highly expressed in both TMJ disc and PDL tissues. Overall, type VI collagen might be a key molecule for TMJ disc regeneration, ensuring elasticity and cushioning, and could provide new insights for TMJ regeneration.
Authors
- Itaru Mizoguchi
- Rie Takai (ORCID: https://orcid.org/0000-0001-7901-3477)
- Toshiya Arakawa (ORCID: https://orcid.org/0000-0001-7504-353X)
- Yoshihiro Abiko (ORCID: https://orcid.org/0000-0001-6358-8508)
- Haruna Kashio
- Ayuko Takada
- Yuya Nakao (ORCID: https://orcid.org/0000-0002-6388-9017)
- Nattakarn Hosiriluck (ORCID: https://orcid.org/0000-0001-8533-5683)
- Masahiro Iijima (ORCID: https://orcid.org/0000-0003-3426-8120)
Institutions
- Health Sciences University of Hokkaido (JP)
- Tohoku University (JP)
- Mahidol University (TH)
Publication Details
- Journal
- Journal of Oral Biology and Craniofacial Research
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1016/j.jobcr.2025.03.018
- Citations
- 1
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.67
Funders
- Ministry of Education, India