HISTOLOGICAL EFFECT OF METHYLE DOPA ON THE LIVER AND KIDNEY OF MALE ALBINO MICE

The current investigation was designed to assess the impact of the aldmet medication on the liver and kidneys of albino male mice.Twenty male mice were utilized as experimental subjects, divided into four groups.The second group received dosage of 125 mg/kg, the third group had been administered 250 mg/kg, the fourth group was treated with 500 mg/kg, and the first group (control) received physiological saline.The duration of the trial is 8 weeks.The study of liver showed clear blood vessels congestion with perivascular leukocytes cuffing in group2, The hepatic tissue shoes clear portal vein congestion with perivascular leukocytes cuffing and decreasing sinusoidal space in group3.While The hepatic tissue shoes clear portal vein congestion with perivascular leukocytes cuffing and decreasing sinusoidal space with clear hepatocytes fatty changes Fatty liver, The study of kidney showed sever bleeding and congestion in the renal section with infiltration of inflammatory cells Suppurative with clear narrowing of the lumen of renal proximal tubules in G2, The renal tissue shoes sever bleeding and congestion in the renal section with infiltration of inflammatory cells (Suppurative nephritis, with clear narrowing of the lumen of renal proximal tubules and hypertrophic lesion