SIDE EFFECTS OF ALDOMET DRUG ON LIVER AND KIDNEY FUNCTIONS IN MALE RATS RATTUS RATTUS

The objective of this research was to investigate the effects of the drug aldmet on the kidney function and liver of male albinos.Drugs like aldomet, which are members of the alpha 2agonists class and which relax muscles and reduce blood pressure, target specific mechanisms that contribute to the onset of hypertension.This study aims to identify the impact of methyl dopa on renal and hepatic function.Twenty four male rats were used as an experimental animals , they are divided into four groups ,the second group treated with dose 125 mg/kg of body weight , the third group was treated with 250mg/kg body, the fourth was treated with 500mg/kg and the first group (control ) receiving physiological normal sline.the period of study 15 weeks.The study of kidney showed e renal tissue shoes sever bleeding and congestion in the renal section with infiltration of inflammatory cells sppurative with clear narrowing of the lumen of renal proximal tubules in G2, The renal tissue shoes sever bleeding and congestion in the renal section with infiltration of inflammatory cells (Suppurative nephritis, with clear narrowing of the lumen of renal proximal tubules and hypertrophic lesion of renal glomeruli