Rational approach to migraine attacks relief

Strategies against migraine attacks include the use of pharmacological agents that are both non-specific and specific for migraine. Despite the wide arsenal of pharmacological agents, effective pain relief is achieved in only one third of migraine patients. When choosing the optimal analgesics for each patient, several key characteristics of the drug should be considered: not only its analgesic effect, but also its ability to rapidly terminate concomitant symptoms without the need for additional analgesics. One of the justified strategies is the combination of specific and nonspecific agents or the use of ready-made combination preparations that allow a multimodal effect in migraine.