An Open Label Single Arm Clinical Study to Evaluate the Combined Effectiveness of Oral Administration of Abhayarishta Churna and Aragwadha Patra Lepa in Kitibha Kushta (Psoriasis)

Kitibha Kushta is a Raktapradoshaja Vikara where it is categorised under Kshudra Kushta. Acharya Charaka mentioned the involvement of Vata and Kapha in Kitibha Kushta and is compared with Psoriasis due to close resemblance of its symptoms. Psoriasis is a chronic inflammatory, non-communicable, painful, disfiguring, disabling, and hyperproliferative skin disease. It is a chronic, non-communicable, proliferative auto-immune skin disease affecting 2% of world population. The prevalence of psoriasis ranges between 0.09% and 11.4% in different populations around the world, making it a serious global concern. In India, the prevalence of psoriasis varies from 0.44 to 2.8%, According to Global Psoriasis Atlas (GPA) an estimated 3.59 million people in India and 100 million people world-wide are affected. Objectives of the study: To evaluate the combined effectiveness of Abhayarishta Churna and Aragwadha Patra Lepa in management of Kitibha Kushta (Psoriasis). Material & Methods: A total of 30 participants of either gender were included in the study using the random sampling method. Among 33 registered participants, 30 completed the course of study. They were administered with Abhayarishta Churna 6 grams twice a day after food with Anupana of Madhu for 30 days in combination with Aragwadha Patra Lepa application externally. Lakshanas of Kitibha Kushta were assessed as primary outcome measures and the PASI score was assessed as the secondary outcome. For statistical analysis, subjective parameters were assessed with Friedman’s test, Wilcoxon sign rank test. Objective parameters were assessed by Repeated Measures ANOVA. Results: Statistically significant improvement was observed in the primary and secondary outcome measures of Kitibha Kushta (Psoriasis). Conclusion: Combination of Abhayarishta Churna and Aragwadha Patra Lepa was found to be effective in the management of Kitibha Kushta (Psoriasis).