A Randomised Prospective Crossover Study on the Effects of Medium Cut-Off Membranes on FGF-23 and Inflammatory Mediators in Patients Receiving Regular Haemodialysis
The use of both MCO and HFD membranes resulted in a significant reduction of FGF-23 levels and other selected inflammatory cytokines. However, the MCO membrane did not demonstrate a significant advantage over the HFD in the short term. There was no significant intrasubject variability for all assessed biomarkers apart from hsCRP. .
Authors
- Darren Green (ORCID: https://orcid.org/0000-0002-9370-8176)
- Dimitrios Poulikakos (ORCID: https://orcid.org/0000-0001-7987-2247)
- Dawn Evans
- Saif Al‐Chalabi (ORCID: https://orcid.org/0000-0003-1669-8514)
- Leon J. Schurgers (ORCID: https://orcid.org/0000-0001-7867-6957)
- Smeeta Sinha (ORCID: https://orcid.org/0000-0003-4117-4085)
- Philip A. Kalra (ORCID: https://orcid.org/0000-0001-7652-1572)
Institutions
- Manchester Academic Health Science Centre (GB)
- University of Manchester (GB)
- Northern Health and Social Care Trust (GB)
- Maastricht University (NL)
- Bradford District Care NHS Foundation Trust (GB)
Publication Details
- Journal
- Blood Purification
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1159/000545745
- Citations
- 2
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.86