Regulation of the Nrf2/HO-1 pathway in chronic obstructive pulmonary disease-induced muscle atrophy using Jinshui Liujian decoction and Bajitian pills: insights from network pharmacology and animal models

Modified Jinshui Liujian decoction and Bajitian pills effectively mitigate muscle atrophy associated with COPD by modulating the Nrf2/HO-1 pathway through multi-target mechanisms. The combined TCM and WM therapy demonstrates enhanced therapeutic efficacy compared to monotherapy.

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Publication Details

Journal
Hereditas
Published
2025-04-21
DOI
https://doi.org/10.1186/s41065-025-00432-5
Citations
1
Primary Topic
Exercise and Physiological Responses
Type
article
Field-Weighted Citation Impact
1.03
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article

Regulation of the Nrf2/HO-1 pathway in chronic obstructive pulmonary disease-induced muscle atrophy using Jinshui Liujian decoction and Bajitian pills: insights from network pharmacology and animal models

Brenda X. Lin, Sheng-Long Wang, Li Bai
1 citations
Hereditas
Exercise and Physiological Responses
1.03
article

Regulation of the Nrf2/HO-1 pathway in chronic obstructive pulmonary disease-induced muscle atrophy using Jinshui Liujian decoction and Bajitian pills: insights from network pharmacology and animal models

Brenda X. Lin, Sheng-Long Wang, Li Bai
article en
1 citations

Abstract

Modified Jinshui Liujian decoction and Bajitian pills effectively mitigate muscle atrophy associated with COPD by modulating the Nrf2/HO-1 pathway through multi-target mechanisms. The combined TCM and WM therapy demonstrates enhanced therapeutic efficacy compared to monotherapy.

HereditasVol. 162(1)
Shanxi University of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 23%
Exercise and Physiological Responses
1.03
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