Late Relapse After Autologous Hematopoietic Stem Cell Transplantation in AQP4-IgG–Positive NMOSD
This case series examines long-term outcomes for 2 aquaporin-4-IgG (AQP4-IgG)–positive patients with neuromyelitis optica spectrum disorder (NMOSD) who underwent autologous hematopoietic stem cell transplantation with a nonmyeloablative conditioning regimen and rituximab.
Authors
- Kyle Blackburn (ORCID: https://orcid.org/0000-0001-5227-153X)
- Sarah M. Jenkins (ORCID: https://orcid.org/0000-0002-4157-8066)
- Eoin P. Flanagan (ORCID: https://orcid.org/0000-0002-6661-2910)
- Nisa Vorasoot (ORCID: https://orcid.org/0000-0002-0751-8967)
- Jiraporn Jitprapaikulsan (ORCID: https://orcid.org/0000-0003-3342-2755)
- Sarosh R. Irani (ORCID: https://orcid.org/0000-0002-7667-9748)
- Melissa Bush
- Linda Nguyen (ORCID: https://orcid.org/0000-0001-7318-4865)
- Sean Joseph Pittock (ORCID: https://orcid.org/0000-0002-6140-5584)
- James P. Fryer
Institutions
- Mayo Clinic (US)
- Siriraj Hospital (TH)
- Khon Kaen University (TH)
- Mahidol University (TH)
- Jacksonville College (US)
- Southwestern Medical Center (US)
- Mayo Clinic in Florida (US)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.5989
- Citations
- 2
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Wellcome Trust
- National Institute for Health and Care Research
- Medical Research Council