Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells

KRTs play a crucial role in the homeostasis and pathological regulation of the corneal epithelium. The stress Krt17 located in LSCs is involved in regulating the stemness, proliferation, and differentiation of LSCs, as well as immune and defense responses.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-04-21
DOI
https://doi.org/10.1167/iovs.66.4.55
Citations
5
Primary Topic
Skin and Cellular Biology Research
Type
article
Field-Weighted Citation Impact
5.76

Funders

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article

Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells

Yizhou Li, Hongqi Ge, Qingjun Zhou, Rui Cao et al.
5 citations
Investigative Ophthalmology & Visual Science
Skin and Cellular Biology Research
5.76
article

Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells

Yizhou Li, Hongqi Ge, Qingjun Zhou, Rui Cao, Min Wang, Ya Li, Xiaolei Wang, Rong Chen, Lingling Yang, Yao Wang
article en
5 citations

Abstract

KRTs play a crucial role in the homeostasis and pathological regulation of the corneal epithelium. The stress Krt17 located in LSCs is involved in regulating the stemness, proliferation, and differentiation of LSCs, as well as immune and defense responses.

Investigative Ophthalmology & Visual ScienceVol. 66(4)
Shandong University (CN), Shandong Eye Hospital (CN), Shandong First Medical University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Shandong Province, National Key Research and Development Program of China
Zero hunger
Openalex Percentile: Top 4%
Skin and Cellular Biology Research
5.76
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Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells — Yizhou Li, Hongqi Ge, et al. · Investigative Ophthalmology & Visual Science (2025) | TGRS Research Map | TGRS