The Exponential Constriction Model of the Ellipsoid Zone in Taiwanese Individuals With RPGR-Related X-Linked Retinitis Pigmentosa
This first longitudinal analysis of RPGR-related RP in Taiwan presents a predictive model of EZ constriction. Findings suggest earlier onset in Exon 1-14 variants and a tendency for faster progression in the ORF15 group, informing insights for genetic therapy development and disease management.
Authors
- Po‐Ting Yeh (ORCID: https://orcid.org/0000-0002-0461-8778)
- Yi-Han Huang
- Chung‐May Yang (ORCID: https://orcid.org/0000-0003-4082-420X)
- Ying-Ju Lai (ORCID: https://orcid.org/0000-0002-5444-4040)
- Tso‐Ting Lai (ORCID: https://orcid.org/0000-0002-8247-7018)
- Ta‐Ching Chen (ORCID: https://orcid.org/0000-0003-4358-6585)
- Chien‐Yu Lin (ORCID: https://orcid.org/0000-0002-6184-8852)
- Yu-Shu Huang (ORCID: https://orcid.org/0000-0002-6997-8424)
- Chang‐Hao Yang (ORCID: https://orcid.org/0000-0002-4328-8716)
- Pei-Lung Chen
- Yi‐Ting Hsieh (ORCID: https://orcid.org/0000-0003-2258-154X)
- Chao‐Wen Lin (ORCID: https://orcid.org/0000-0001-5766-3057)
- Tzzy‐Chang Ho
Institutions
- National Taiwan University (TW)
- University of Pittsburgh (US)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1167/iovs.66.4.59
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00