Abstract 4067: Covaris truCOVER library prep kit: A streamlined PCR free WGS workflow for enhanced NGS library performance and data quality

Abstract Whole-genome sequencing (WGS) has become an indispensable tool in genomic research and clinical diagnostics, offering unprecedented insights into the underlying mechanisms of genetic diseases, cancer evolution, pharmacogenetics and pharmacology References: (1). Rosenquist et al., Clinical Utility of Whole-Genome Sequencing in Precision Oncology. Seminars in Cancer Biology, 84, 32-39 (2022).(2). Process et al., Optimization of Insert Sizes for Illumina’s WGS with Covaris AFA-Based Shearing and Bead-Based Size Selection. Covaris Application Note (2024). Citation Format: Vanessa Process, Martina Werner, Madan Ambavaram, Thuy Dao, Heidi Giese, Sushant Khanal, Luca Beker, Sameer Vasantgadkar, Maura Berkeley, Zachary Herbert, Greg Endress, Eugenio Daviso, Ulrich Thomann. Covaris truCOVER library prep kit: A streamlined PCR free WGS workflow for enhanced NGS library performance and data quality [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr 25-30; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2025;85(8_Suppl_1):Abstract nr 4067.