Functional protein biomarkers based on distributions of expression levels in single-cell imaging data

The associated R package Qindex is available at https://CRAN.R-project.org/package=Qindex and R package hyper.gam is available at https://github.com/tingtingzhan/hyper.gam. Examples of R code and detailed instructions could be found in vignette quantile-index-predictor (https://CRAN.R-project.org/package=hyper.gam/vignettes/applications.html#quantile-index-predictor).

Authors

Misung Yi (ORCID: https://orcid.org/0000-0002-4007-5408)
Inna Chervoneva (ORCID: https://orcid.org/0000-0002-9104-4505)
Tingting Zhan (ORCID: https://orcid.org/0000-0001-9971-4844)
Hallgeir Rui (ORCID: https://orcid.org/0000-0002-8778-261X)

Institutions

Thomas Jefferson University (US)
Sidney Kimmel Cancer Center (US)
Dankook University (KR)

Publication Details

Journal: Bioinformatics
Published: 2025-04-21
DOI: https://doi.org/10.1093/bioinformatics/btaf182
Primary Topic: Single-cell and spatial transcriptomics
Type: article
Field-Weighted Citation Impact: 0.00

Funders

National Cancer Institute

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article

Functional protein biomarkers based on distributions of expression levels in single-cell imaging data

Misung Yi, Inna Chervoneva, Tingting Zhan, Hallgeir Rui

Apr 21, 2025

Bioinformatics

Single-cell and spatial transcriptomics

article

Functional protein biomarkers based on distributions of expression levels in single-cell imaging data

Misung Yi, Inna Chervoneva, Tingting Zhan, Hallgeir Rui

April 21, 2025article en

Abstract

The associated R package Qindex is available at https://CRAN.R-project.org/package=Qindex and R package hyper.gam is available at https://github.com/tingtingzhan/hyper.gam. Examples of R code and detailed instructions could be found in vignette quantile-index-predictor (https://CRAN.R-project.org/package=hyper.gam/vignettes/applications.html#quantile-index-predictor).

BioinformaticsVol. 41(5)

Thomas Jefferson University (US), Sidney Kimmel Cancer Center (US), Dankook University (KR)

National Cancer Institute

Good health and well-being

Openalex Percentile: Top 93%

Single-cell and spatial transcriptomics

DOI Open Access PDF OpenAlex

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Functional protein biomarkers based on distributions of expression levels in single-cell imaging data — Misung Yi, Inna Chervoneva, et al. · Bioinformatics (2025) | TGRS Research Map | TGRS