Phosphoproteomics Uncovers Exercise Intensity-Specific Skeletal Muscle Signaling Networks Underlying High-Intensity Interval Training in Healthy Male Participants
Collectively, this first global map of the work-matched HIIT versus MICT signaling networks has revealed rapid exercise intensity-specific regulation of kinases, substrates, and pathways in human skeletal muscle that may contribute to HIIT's skeletal muscle adaptations and health-promoting effects. Preprint: The preprint version of this work is available on medRxiv, https://doi.org/10:1101/2024.07.11.24310302 .
Authors
- Nolan J. Hoffman (ORCID: https://orcid.org/0000-0001-5168-7082)
- Di Xiao (ORCID: https://orcid.org/0000-0003-2419-7840)
- Benjamin L. Parker (ORCID: https://orcid.org/0000-0003-1818-2183)
- John A. Hawley (ORCID: https://orcid.org/0000-0002-0886-9881)
- Ronnie Blazev (ORCID: https://orcid.org/0000-0002-2509-3907)
- Bridget E. Radford (ORCID: https://orcid.org/0000-0003-4528-1988)
- Jamie Whitfield (ORCID: https://orcid.org/0000-0002-8961-8872)
- Veronika Suni (ORCID: https://orcid.org/0000-0001-8269-7291)
- Pengyi Yang (ORCID: https://orcid.org/0000-0003-1098-3138)
Institutions
- Manchester Metropolitan University (GB)
- The University of Sydney (AU)
- Children's Medical Research Institute (AU)
- Charles Sturt University (AU)
- The University of Melbourne (AU)
- Australian Catholic University (AU)
Publication Details
- Journal
- Sports Medicine
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1007/s40279-025-02217-2
- Citations
- 10
- Primary Topic
- Cardiovascular and exercise physiology
- Type
- article
- Field-Weighted Citation Impact
- 23.81
Funders
- Australian Catholic University
- Australian Research Council
- National Health and Medical Research Council