Is FLAIRectomy Directly Correlated with Prolonged Survival in Glioblastoma? A Prospective National Multicenter Study on Correlation Between Extent of Tumor Resection and Clinical Outcome
This multicenter study demonstrates that EOFR is a more reliable predictor of PFS and OS than extent of resection based on gadolinium-enhanced T1 sequences, if supramarginal resection is performed according to specific preoperative planning. 3-dimensional FLAIR navigation-guided resection may represent the optimal strategy to achieve a real FLAIRectomy.
Authors
- G Ferranti (ORCID: https://orcid.org/0009-0005-1862-9856)
- Gaetano Magro (ORCID: https://orcid.org/0000-0003-3244-6827)
- Francesco Certo (ORCID: https://orcid.org/0000-0002-6346-2769)
- Massimiliano Visocchi (ORCID: https://orcid.org/0000-0003-1087-0491)
- Alessandro Pluchino (ORCID: https://orcid.org/0000-0001-9368-5800)
- Antonio Melcarne (ORCID: https://orcid.org/0000-0002-1925-2641)
- Antonella Agodi (ORCID: https://orcid.org/0000-0002-4405-8162)
- Alessandro Olivi (ORCID: https://orcid.org/0000-0002-4489-7564)
- Giuseppe Barbagallo (ORCID: https://orcid.org/0000-0002-7760-6700)
- Andrea Maugeri (ORCID: https://orcid.org/0000-0003-2655-8574)
- Giuseppe Broggi (ORCID: https://orcid.org/0000-0003-2576-6523)
- Andrea Rapisarda (ORCID: https://orcid.org/0000-0001-8290-8183)
- Rosario Caltabiano (ORCID: https://orcid.org/0000-0001-8591-8010)
- Diego Garbossa (ORCID: https://orcid.org/0000-0002-2692-7133)
- Giuseppe Maria Della Pepa (ORCID: https://orcid.org/0000-0001-8698-3359)
- Giuseppe La Rocca (ORCID: https://orcid.org/0000-0003-1830-4849)
- Roberta Rudà (ORCID: https://orcid.org/0000-0001-9134-1537)
- Giovanni Sabatino (ORCID: https://orcid.org/0000-0002-4227-0434)
- Vincenzo Albanese
Institutions
- Agostino Gemelli University Polyclinic (IT)
- University of Catania (IT)
- Complexity Science Hub (AT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Turin (IT)
Publication Details
- Journal
- Neurosurgery
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1227/neu.0000000000003453
- Citations
- 2
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.25