The Medical Management of Interstitial Pregnancy: A Case Series and Literature Review

Introduction: Interstitial pregnancies are a rare form of ectopic pregnancy, and their diagnosis and treatment can be challenging. Results: This case series presents three cases of interstitial pregnancies successfully treated with intramuscular methotrexate. Conclusion: Methotrexate is an effective treatment for interstitial pregnancies, even in cases with high β-hCG levels or fetal cardiac activity. For patients who can be closely monitored, medical treatment provides a good alternative to surgery.