Advancing Understanding of Cerebrovascular Hemodynamic Perturbations in Pediatric Cerebral Malaria Using a Modified Critical Closing Pressure Evaluation- A Prospective, Observational Study
CrCP was > 1SD lower or higher than the mean normal value in a significant number of children with CM. A low DCM is associated with a worse prognosis and may serve as a therapeutic target.
Authors
- Mengxin Yu (ORCID: https://orcid.org/0000-0002-6818-4083)
- Terrie E. Taylor (ORCID: https://orcid.org/0000-0001-7416-3986)
- Montfort Bernard Gushu
- Nicole O’Brien
- Karl B. Seydel (ORCID: https://orcid.org/0000-0001-9859-9549)
- Madiha Q. Raees
- Tusekile Phiri
- Sylvester June
- Dylan S. Small (ORCID: https://orcid.org/0000-0003-4928-2646)
- Hunter Wynkoop
Institutions
- Philadelphia College of Osteopathic Medicine (US)
- University of the Sciences (US)
- Nationwide Children's Hospital (US)
- Children's Hospital of Philadelphia (US)
- Queen Elizabeth Central Hospital (MW)
- The Ohio State University (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Neurocritical Care
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1007/s12028-025-02245-w
- Citations
- 1
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 1.39