Reducing Cabozantinib Toxicity in Renal Cell Carcinoma Treatment through Structural Modifications
These findings provide structural insights into cabozantinib's dual effects and suggest optimization strategies for TKI design, offering a pathway toward safer and more effective RCC treatments.
Authors
- Jiaxiang Guo
- Yongliang Lu
- Xiaotao Yin
- Yang Yu (ORCID: https://orcid.org/0000-0002-2480-7306)
Institutions
- Chinese PLA General Hospital (CN)
Publication Details
- Journal
- Medicinal Chemistry
- Published
- 2025-04-21
- DOI
- https://doi.org/10.2174/0115734064374511250411104320
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00