Pharmacokinetic/Pharmacodynamic Analysis of Extended/Two-Step Infusion Ceftazidime/Avibactam in Children With Gram-Negative Bacterial Infections
The current STD of CZA may not adequately meet the therapeutic requirements in children, thus it is recommended to optimize the dosing regimen by extended/two-step infusion or increasing the daily dose, guided by therapeutic drug monitoring.
Authors
- Ruiying Han
- Weihua Zhang (ORCID: https://orcid.org/0000-0003-2680-6814)
- Zhi Yuan (ORCID: https://orcid.org/0000-0002-5847-2823)
- Ying Zhang (ORCID: https://orcid.org/0000-0002-7283-0578)
- Dan Sun (ORCID: https://orcid.org/0000-0002-6249-5999)
- Baosen Yue
Institutions
- Shaanxi Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Clinical Therapeutics
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1016/j.clinthera.2025.03.008
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00