High Throughput Pharmacovigilance Screening for Roflumilast Adverse Effects in Real‐World Settings: A Sequence Symmetry Analysis
In our study, we detected 32 safety signals for roflumilast, including notable associations with antithyroid agents and parathyroid hormones. Future investigations using more robust study designs are warranted to evaluate those signals.
Authors
- Charles Gaber (ORCID: https://orcid.org/0000-0002-6752-2968)
- Todd A. Lee (ORCID: https://orcid.org/0000-0003-3619-5367)
- Abdullah Abdelaziz (ORCID: https://orcid.org/0000-0002-5039-4322)
- Preeti Gupta (ORCID: https://orcid.org/0000-0001-9972-2123)
Institutions
- University of Illinois Chicago (US)
Publication Details
- Journal
- Basic & Clinical Pharmacology & Toxicology
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1111/bcpt.70038
- Citations
- 2
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 2.61