Silent Thyroiditis Presented as Transient Hypothyroidism During Pregnancy: A Case Report

Silent thyroiditis during pregnancy is an under-recognized clinical condition and arare case, often manifesting as transient hypothyroidism. We report a 23-year-oldwoman at 8 weeks of gestation who presented with newly diagnosed hypothyroidism[TSH = 85 mIU/L (0.4–4.5), FT4 = 0.4 ng/dL (0.7–2.5), and anti-TPO = 78 IU/mL (upto 16)]. Thyroid function tests had been normal eight months prior. Levothyroxine(LT4) therapy was initiated, restoring euthyroidism. Treatment was discontinuedpostpartum, and the patient maintained normal thyroid function for over one year.Our case is unique in that silent thyroiditis occurred unusually early in pregnancyand differed from the more common postpartum cases. Silent thyroiditis should beconsidered in pregnancy-related hypothyroidism, particularly when prior thyroidfunction was normal. Prompt diagnosis and treatment can prevent adverse maternaland fetal outcomes

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Publication Details

Journal
Case Reports in Clinical Practice
Published
2025-04-21
DOI
https://doi.org/10.18502/crcp.v9i5.18453
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Silent Thyroiditis Presented as Transient Hypothyroidism During Pregnancy: A Case Report

Shahin Nosratzehi, Mahmoud Ali Kaykhaei
Case Reports in Clinical Practice
Thyroid Disorders and Treatments
article

Silent Thyroiditis Presented as Transient Hypothyroidism During Pregnancy: A Case Report

Shahin Nosratzehi, Mahmoud Ali Kaykhaei
article en

Abstract

Silent thyroiditis during pregnancy is an under-recognized clinical condition and arare case, often manifesting as transient hypothyroidism. We report a 23-year-oldwoman at 8 weeks of gestation who presented with newly diagnosed hypothyroidism[TSH = 85 mIU/L (0.4–4.5), FT4 = 0.4 ng/dL (0.7–2.5), and anti-TPO = 78 IU/mL (upto 16)]. Thyroid function tests had been normal eight months prior. Levothyroxine(LT4) therapy was initiated, restoring euthyroidism. Treatment was discontinuedpostpartum, and the patient maintained normal thyroid function for over one year.Our case is unique in that silent thyroiditis occurred unusually early in pregnancyand differed from the more common postpartum cases. Silent thyroiditis should beconsidered in pregnancy-related hypothyroidism, particularly when prior thyroidfunction was normal. Prompt diagnosis and treatment can prevent adverse maternaland fetal outcomes

Case Reports in Clinical Practice
Zahedan University of Medical Sciences (IR)
Openalex Percentile: Top 89%
Thyroid Disorders and Treatments
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Silent Thyroiditis Presented as Transient Hypothyroidism During Pregnancy: A Case Report — Shahin Nosratzehi, Mahmoud Ali Kaykhaei · Case Reports in Clinical Practice (2025) | TGRS Research Map | TGRS