Impact of growth hormone therapy on bone and body composition in prepubertal children with idiopathic short stature

Prepubertal children with ISS exhibited lower BMAD at the lumbar spine compared to healthy controls. Although short-term GH therapy did not significantly alter bone density, it positively impacted body composition. These findings provide valuable clinical insights into bone health and body composition in children with ISS.

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Publication Details

Journal
Journal of Pediatric Endocrinology and Metabolism
Published
2025-04-21
DOI
https://doi.org/10.1515/jpem-2025-0085
Primary Topic
Growth Hormone and Insulin-like Growth Factors
Type
article
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0.00
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article

Impact of growth hormone therapy on bone and body composition in prepubertal children with idiopathic short stature

Soon‐Jin Hwang, Hae Sang Lee, Young Suk Shim, Min Hyung Cho et al.
Journal of Pediatric Endocrinology and Metabolism
Growth Hormone and Insulin-like Growth Factors
article

Impact of growth hormone therapy on bone and body composition in prepubertal children with idiopathic short stature

Soon‐Jin Hwang, Hae Sang Lee, Young Suk Shim, Min Hyung Cho, Se Jin An
article en

Abstract

Prepubertal children with ISS exhibited lower BMAD at the lumbar spine compared to healthy controls. Although short-term GH therapy did not significantly alter bone density, it positively impacted body composition. These findings provide valuable clinical insights into bone health and body composition in children with ISS.

Journal of Pediatric Endocrinology and MetabolismVol. 38(6)
Ajou University Hospital (KR), Ajou University (KR)
Good health and well-being
Openalex Percentile: Top 89%
Growth Hormone and Insulin-like Growth Factors
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