Deciphering the relationship between sarcopenia and aging: A combined text mining and bioinformatics approach

A comprehensive bioinformatics analysis, complemented by the text mining of the extant literature, suggested that sarcopenia might not be characterized by a failure of autophagy as a whole, but rather, by a disruption of oxidative stress regulation, particularly nicotinamide adenine dinucleotide phosphate oxidase catalytic subunit-related pathways at a subsequent stage of autophagy after phagosome-lysosome fusion. Geriatr Gerontol Int 2025; 25: 806-814.