Disrupted small-world networks in children with drug-naïve growth hormone deficiency: a DTI-based network analysis
Our findings reveal disrupted WM topological organization in children with GHD, which may potentially relate to abnormal GH/IGF-1 levels and associated with behavioral problems. These alterations in structural brain networks may underlie the behavioral challenges observed in GHD, providing new insights into the neurobiological basis of this condition.
Authors
- Yang Zhang (ORCID: https://orcid.org/0000-0001-7643-3492)
- Long Qian (ORCID: https://orcid.org/0000-0002-1346-0810)
- Wei Cui (ORCID: https://orcid.org/0000-0003-2245-6052)
- Long Zhang (ORCID: https://orcid.org/0000-0002-2185-6890)
- Qiuli Chen (ORCID: https://orcid.org/0000-0002-9550-7327)
- Li‐Ping Lin
- Huaqiong Qiu
- L. Wu (ORCID: https://orcid.org/0009-0006-2108-0144)
- Yuli Cheng (ORCID: https://orcid.org/0000-0003-4464-3684)
- Shu Su (ORCID: https://orcid.org/0000-0001-8704-9752)
- Xianhong Xiang
- Yasen Alimire
Institutions
- Sun Yat-sen University (CN)
- Peking University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Quantitative Imaging in Medicine and Surgery
- Published
- 2025-04-21
- DOI
- https://doi.org/10.21037/qims-24-1927
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00