Synthesis of the Proposed Structure of Urupocidin A
The proposed structure of urupocidin A was synthesized. The bicyclic guanidino core was constructed by Pd(II) catalyzed cyclization-carbonylation-cyclization cascade reactions of the acyclic propargyl guanidine. The <i>N</i>-hydroxy guanidino functionality was protected as a THP ether.
Authors
- Kyoka Someya
- Takuya Tsukamoto
- Keisuke Takahashi (ORCID: https://orcid.org/0000-0002-1438-9091)
- Keisuke Kato (ORCID: https://orcid.org/0000-0003-4408-4181)
- Taichi Kusakabe
Institutions
- Toho University (JP)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1021/acs.orglett.5c01046
- Primary Topic
- Chemical synthesis and alkaloids
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education, Culture, Sports, Science and Technology