Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin
Greatly elevated bHCG levels and age > 40 years are significantly associated with poor semen quality in GCT patients. The inverse association of age with semen quality is a novel finding in GCT patients that mirrors the physiological decline of male reproductive function with age but that still needs confirmation. As these two features are present in only a small proportion of patients, other factors such as the postulated testicular dysgenesis syndrome may be involved in the pathogenesis of poor semen quality in the majority of GCT patients.
Authors
- Andrea Salzbrunn
- Christian Ruf
- Cord Matthies (ORCID: https://orcid.org/0000-0001-5540-2099)
- Kathrein von Kopylow (ORCID: https://orcid.org/0000-0003-4362-7973)
- Christian Wülfing (ORCID: https://orcid.org/0000-0002-0251-2654)
- Armin Soave (ORCID: https://orcid.org/0009-0006-4552-4934)
- Uwe Pichlmeier
- Klaus‐Peter Dieckmann (ORCID: https://orcid.org/0000-0002-3821-7956)
- Magdalena Godlewska (ORCID: https://orcid.org/0000-0002-1891-7859)
- Johanna Hochmuth‐Tisch
Institutions
- Universität Hamburg (DE)
- Asklepios Klinik Altona (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Bundeswehrkrankenhaus (DE)
- Bundeswehrkrankenhaus Ulm (DE)
Publication Details
- Journal
- Andrology
- Published
- 2025-04-20
- DOI
- https://doi.org/10.1111/andr.70046
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00