New Possibilities for Overcoming Antibiotic Resistance in Bacteria

Antibiotic resistance remains one of the most significant barriers to successful treatment of bacterial diseases. The microorganisms present in biofilms develop antimicrobial resistance much faster and more powerfully than planktonic forms. With the help of «quorum sensing», bacteria in biofilms exchange information with each other to maximize their pathogenicity. This review examines the main mechanisms of antibiotic resistance, the structure and vital activity of biofilms, the mechanisms of the «sense of quorum», as well as possible ways to overcome antibiotic-resistant bacterial resistance due to the effect of suppressing the «sense of quorum».