A Common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice

This mouse strain provides evidence that the exon 6 deletion causes ER stress and inflammation and is an excellent model to understand its contribution to pancreatic cancer and identify preventive strategies.

Authors

Institutions

Publication Details

Journal
Gut
Published
2025-04-19
DOI
https://doi.org/10.1136/gutjnl-2024-333406
Citations
6
Primary Topic
Pancreatitis Pathology and Treatment
Type
article
Field-Weighted Citation Impact
12.04

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A Common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice

Evangelina López de Maturana, Marina Malumbres, Katelyn E. Connelly, Brice Chanez et al.
6 citations
Gut
Pancreatitis Pathology and Treatment
12.04
article

A Common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice

Evangelina López de Maturana, Marina Malumbres, Katelyn E. Connelly, Brice Chanez, Irene Felipe‐Abrio, Sagrario Ortega, Núria Malats, Miguel Lafarga, Laufey T. Ámundadóttir, Raúl Méndez, Isabel Peset, Ana Cayuela, Francisco X. Real, Natalia del Pozo, Pierfrancesco Vargiu, Jason W. Hoskins, Jaime Martínez de Villarreal, Cristina Bodas
article en
6 citations

Abstract

This mouse strain provides evidence that the exon 6 deletion causes ER stress and inflammation and is an excellent model to understand its contribution to pancreatic cancer and identify preventive strategies.

GutVol. 74(9)
Institució Catalana de Recerca i Estudis Avançats (ES), Universidad de Cantabria (ES), Universitat Pompeu Fabra (ES), Spanish National Cancer Research Centre (ES), Instituto de Investigación Biomédica de Lleida (ES), National Cancer Institute (US), Centro Nacional de Microelectrónica (ES), Molecular Oncology (United States) (US), Institut Paoli-Calmettes (FR), Division of Cancer Epidemiology and Genetics
Ministerio de Ciencia, Innovación y Universidades
Good health and well-being
Openalex Percentile: Top 1%
Pancreatitis Pathology and Treatment
12.04
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.